Lighttpd
img\.griefcraft\.com would of course become whatever your image domain is

$HTTP["host"] =~ "^(img\.griefcraft\.com|puush\.me)$" {
        server.document-root = "/var/www/servers/img.griefcraft.com/"
        url.rewrite-once = (
                "^/api/up" => "/upload.php",
                "^/([a-zA-Z0-9]+)$" => "/view.php?image=$1"
        )
}