diff --git a/include/curl/system.h b/include/curl/system.h
index 973c73ad4..e808580eb 100644
--- a/include/curl/system.h
+++ b/include/curl/system.h
@@ -442,9 +442,6 @@
 /* CURL_PULL_WS2TCPIP_H is defined above when inclusion of header file  */
 /* ws2tcpip.h is required here to properly make type definitions below. */
 #ifdef CURL_PULL_WS2TCPIP_H
-#  ifndef WIN32_LEAN_AND_MEAN
-#    define WIN32_LEAN_AND_MEAN
-#  endif
 #  include <windows.h>
 #  include <winsock2.h>
 #  include <ws2tcpip.h>
diff --git a/lib/curl_setup.h b/lib/curl_setup.h
index eb4f038dd..fc597d75d 100644
--- a/lib/curl_setup.h
+++ b/lib/curl_setup.h
@@ -31,6 +31,17 @@
 #define WIN32
 #endif
 
+#ifdef WIN32
+/*
+ * Don't include unneeded stuff in Windows headers to avoid compiler
+ * warnings and macro clashes.
+ * Make sure to define this macro before including any Windows headers.
+ */
+#  ifndef WIN32_LEAN_AND_MEAN
+#    define WIN32_LEAN_AND_MEAN
+#  endif
+#endif
+
 /*
  * Include configuration script results or hand-crafted
  * configuration file for platforms which lack config tool.
@@ -237,9 +248,6 @@
 #  if defined(_UNICODE) && !defined(UNICODE)
 #    define UNICODE
 #  endif
-#  ifndef WIN32_LEAN_AND_MEAN
-#    define WIN32_LEAN_AND_MEAN
-#  endif
 #  include <windows.h>
 #  ifdef HAVE_WINSOCK2_H
 #    include <winsock2.h>
diff --git a/winbuild/MakefileBuild.vc b/winbuild/MakefileBuild.vc
index eb28efefd..1d8210b3d 100644
--- a/winbuild/MakefileBuild.vc
+++ b/winbuild/MakefileBuild.vc
@@ -60,7 +60,7 @@ CFLAGS     = /I. /I../lib /I../include /nologo /W3 /GX /DWIN32 /YX /FD /c /DBUIL
 !ELSE
 CC_NODEBUG  = $(CC) /O2 /DNDEBUG
 CC_DEBUG    = $(CC) /Od /D_DEBUG /RTC1 /Z7 /LDd /W3
-CFLAGS      = /I. /I ../lib /I../include /nologo /W3 /EHsc /DWIN32 /FD /c /DBUILDING_LIBCURL /DWIN32_LEAN_AND_MEAN
+CFLAGS      = /I. /I ../lib /I../include /nologo /W3 /EHsc /DWIN32 /FD /c /DBUILDING_LIBCURL
 !ENDIF
 
 LFLAGS     = /nologo /machine:$(MACHINE)