diff --git a/include/curl/curl.h b/include/curl/curl.h
index 2d4201f17..0ac3f28ea 100644
--- a/include/curl/curl.h
+++ b/include/curl/curl.h
@@ -65,9 +65,11 @@ extern "C" {
  * We want the typedef curl_off_t setup for large file support on all
  * platforms. We also provide a CURL_FORMAT_OFF_T define to use in *printf
  * format strings when outputting a variable of type curl_off_t.
+ *
+ * Note: "pocc -Ze" is MSVC compatibily mode and this sets _MSC_VER!
  */
 
-#if defined(_MSC_VER) || (defined(__LCC__) && defined(WIN32))
+#if (defined(_MSC_VER) && !defined(__POCC__)) || (defined(__LCC__) && defined(WIN32))
 /* MSVC */
 #ifdef _WIN32_WCE
   typedef long curl_off_t;
@@ -76,7 +78,7 @@ extern "C" {
   typedef signed __int64 curl_off_t;
 #define CURL_FORMAT_OFF_T "%I64d"
 #endif
-#else /* _MSC_VER || (defined(__LCC__) && defined(WIN32)) */
+#else /* (_MSC_VER && !__POCC__) || (__LCC__ && WIN32) */
 #if (defined(__GNUC__) && defined(WIN32)) || defined(__WATCOMC__)
 /* gcc on windows or Watcom */
   typedef long long curl_off_t;
@@ -108,7 +110,7 @@ extern "C" {
 #define CURL_FORMAT_OFF_T "%ld"
 #endif
 #endif /* GCC or Watcom on Windows */
-#endif /* _MSC_VER || (defined(__LCC__) && defined(WIN32)) */
+#endif /* (_MSC_VER && !__POCC__) || (__LCC__ && WIN32) */
 
 #ifdef UNDEF_FILE_OFFSET_BITS
 /* this was defined above for our checks, undefine it again */
@@ -400,7 +402,8 @@ typedef enum {
  * platforms.
  */
 #if defined(__STDC__) || defined(_MSC_VER) || defined(__cplusplus) || \
-  defined(__HP_aCC) || defined(__BORLANDC__) || defined(__LCC__)
+  defined(__HP_aCC) || defined(__BORLANDC__) || defined(__LCC__) || \
+  defined(__POCC__)
   /* This compiler is believed to have an ISO compatible preprocessor */
 #define CURL_ISOCPP
 #else